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US 2007/0166724 A1Published application
Micrornas and related nucleic acids
OwnerItzhak Bentwich, Amir Avniel +2inventors
InventorsItzhak Bentwich, Amir Avniel, Yael Karov, Ranit Aharonov
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Abstract
Described herein are novel polynucleotides associated with disease. The polynucleotides are miRNAs, miRNA precursors, and associated nucleic acids. Methods and compositions are described that can be used for diagnosis, prognosis, and treatment of disease. Also described herein are methods that can be used to identify modulators of the disease-associated polynucleotides.
Claims13
An isolated nucleic acid comprising a sequence selected from the group consisting of:
- (a) any one of SEQ ID NOS:
- 3-7;
- (b) complement of (a);
- and
- (c) sequence at least about 81% identical to 21 contiguous nucleotides of (a) or (b);
- wherein the nucleic acid is from 17-250 nucleotides in length.
3 more elements
Dependencies are inferred from the claim text.