Transdermal and transmucosal preparations
OwnerShuji Sakuma, Kiminori Atsumi +1inventors
InventorsShuji Sakuma, Kiminori Atsumi, Keiichiro Kikukawa
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Abstract
Transdermal and transmucosal preparations are often insufficiently absorbed. Thus, there is a need for additives that can enhance the transdermal and/or transmucosal absorption of various drugs. The present invention provides compositions for enhancing transdermal and/or transmucosal absorption, comprising a hydroxyapatite and essential ingredients. The hydroxyapatite has a maximum particle size of 1 μm or less, preferably 0.1 μm or less, and the content of the hydroxyapatite relative to a drug to be formulated ranges from 0.1 to 1000 weight percent.
Claims18
A transdermal preparation comprising an ingredient to be absorbed transdermally and a hydroxyapatite.
A transmucosal preparation comprising an ingredient to be absorbed transmucosally and a hydroxyapatite.
Dependencies are inferred from the claim text.