Matrix, cell implantation and method for their production and use
AssigneeHumanautocell GmbH
InventorsMartin Goerne, Peter Kaufmann
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Abstract
The invention relates to porous matrices based on a biologically compatible polymer or polymer mixture, to a cell implantation that is established on said matrices and to additional cell implantation based on cell mixtures of hepatocytes and islets of Langerhans. The invention also relates to a method for producing porous matrices, to matrices obtained according to said method and to a special method for obtaining cells for the inoculation of an implantable matrix.
Claims33
1-45. (canceled)
A porous matrix based on a biologically tolerated polymer or polymer mixture, wherein the matrix possesses pores having a size of 150 μm or less and pores having a size of 300 μm or more and the degree of porosity is from 93 to 98%.
A method for preparing a porous matrix based on a biologically degradable polymer or polymer mixture, wherein a mixture comprising polymer particles having a grain size in the range of from about 20 to 950 μm and sodium chloride particles having a grain size in the range of from about 90 to 670 μm, is compacted and the sodium chloride is then dissolved from the mixture.
A method for preparing a porous matrix based on a biologically tolerated polymer or polymer mixture, wherein a mixture composed of polymer particles, particles of a porogenic material and a polymer solution is compacted and the porogenic material is then dissolved from the mixture.
Dependencies are inferred from the claim text.