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AssigneeFolia Biotech Inc.
InventorsDenis Leclerc, Nathalie Majeau, Philippe Tessier, Constantino III Lopez-Macias, Alain Lamarre, Rejean Lapointe
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An immunopotentiating composition comprising a papaya mosaic virus (PapMV), or a virus-like particle (VLP) derived from PapMV coat protein, which is capable of functioning as an adjuvant and thus potentiating an immune response in an animal is provided. The immunopotentiating composition can further comprise an immunogen, which can be fused or otherwise linked to the VLP, or not linked to the VLP. The immunopotentiating composition is capable of potentiating a humoral and/or a cellular response in the animal and is suitable for use as an adjuvant or vaccine. Methods of potentiating an immune response in an animal comprising administering to the animal an immunopotentiating composition are also provided have application in both human and veterinary medicine.
An immunopotentiating composition comprising papaya mosaic virus (PapMV), or a virus-like particle (VLP) derived from PapMV coat protein, wherein said PapMV or said VLP is capable of potentiating an immune response in an animal.
A polynucleotide encoding a PapMV coat protein, said PapMV coat protein being capable of multimerization to form a virus-like particle (VLP).
Dependencies are inferred from the claim text.