Treatment for embolic stroke
AssigneeThe Regents of the University of California
InventorPaul Lapchak
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Abstract
Provided herein are methods and compositions for treating stroke that include contacting a subject suffering from a stroke with (1) an antioxidant; (2) an antioxidant and one or more of (i) a thrombolytic agent, (ii) an NMDA receptor antagonist and (iii) a spin trap agent; or (3) a thrombolytic agent in combination with one or more of (i) an NMDA receptor antagonist and (ii) a spin trap agent.
Claims22
A method of treating stroke comprising:
- contacting a subject suffering from a stroke with an effective amount of an antioxidant polyphenol compound, wherein the subject has improved behavioral outcome compared to a subject that did not receive an antioxidant polyphenol compound.
A formulation comprising a polyphenol antioxidant and at least one agent selected from the group consisting of a thrombolytic agent, an NMDA receptor antagonist, a spin trap agent, and any combination thereof.
Dependencies are inferred from the claim text.