Method for the treatment of bone disorders
AssigneeThe Procter & Gamble Company
InventorsPamela Schofield, Henry Van den Berg, David Burgio, Arkadi Chines
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Abstract
Disclosed are methods for treating bone disorders in mammals. The methods comprise a loading period with a bisphosphonate followed by a maintenance period. The loading dose is two to twenty times per day greater than the corresponding maintenance dose. Also disclosed are compositions and kits for implementing the methods disclosed herein.
Claims20
A method of increasing bone mass in a human or other animal with high bone turnover comprising the steps of
- (a) administering a loading dose for about 7 days to about 180 days of a bisphosphonate;
- and
- (b) administering after step (a) a continuous maintenance dose of a bisphosphonate, wherein the loading dose is from about two times to about twenty times greater than the maintenance dose.
A kit for use in the treatment of increasing bone mass according to a regimen comprising unit doses of bisphosphonate for a loading period and unit doses of a bisphosphonate for a maintenance period which follows the loading period.
Dependencies are inferred from the claim text.