Data processing system for compartmental analysis
AssigneeKoninklijke Philips Electronics N.V.
InventorsTimo Paulus, Dragos-Nicolae Peligrad, Lothar Spies
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AssigneeKoninklijke Philips Electronics N.V.
InventorsTimo Paulus, Dragos-Nicolae Peligrad, Lothar Spies
Estimating the term…
The invention relates to a data processing system (1) for the evaluation of image data, particularly of PET-images (I), that represent the time varying concentration of a tracer substance like F-MISO in an object (20). The data processing system (1) comprises a library module (48) with analytical solutions (Cj(t)) for several compartment models. Preferably the library also contains the analytical gradients with respect to the parameters of interest. From the library an appropriate solution for each study can be chosen by a user. The use of analytical functions together with the information about the error (σA(t)) of the input data (either via noise models 43 or via a simulation 44) allows to extract all parameters mandatory to fully understand the kinetics of complex models (more than one tissue compartment) on a per-voxel basis in a robust way in real-time.
A data processing system (1) for the evaluation of image data (I) that represent the time varying concentration (A(t)) of at least one tracer substance in an object (20), comprising
A record carrier on which a computer program for the evaluation of image data (I) that represent the time varying concentration (A(t)) of at least one tracer substance in an object (20) is stored, wherein said program is adapted to fit the parameters (K1, k2, . . . ) of analytical functions which represent solutions to at least one given physiological compartment model to said image data (I).
Dependencies are inferred from the claim text.