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AssigneeThe Regents of the University of Michigan
InventorsJosef Miller, Colleen LePrell, Jochen Schacht, Diane Prieskorn
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A composition for treating hearing loss includes components that function through different biological mechanisms to provide an additive effect that is equal to or greater than a sum of the effect of the individual components. The composition includes a biologically effective amount of at least one scavenger of singlet oxygen, a donor antioxidant, a third antioxidant, and a vasodilator. A method of treating hearing loss includes the step of internally administering the composition including a biologically effective amount of the at least one scavenger of singlet oxygen, the donor antioxidant, the third antioxidant, and the vasodilator to a mammal within three days of trauma to a middle or inner ear of the mammal.
A method of treating hearing loss comprising the step of internally administering a composition to a mammal including a biologically effective amount of at least one scavenger of singlet oxygen, a donor antioxidant, a third antioxidant, and a vasodilator within three days of trauma to a middle or inner ear of the mammal to provide an additive effect that is equal to or greater than a sum of the effects of the individual components.
A composition for treating hearing loss including components that function through different biological mechanisms to provide an additive effect that is greater than a sum of the effect of the individual components, said composition comprising:
Dependencies are inferred from the claim text.