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US 2007/0164133 A1Published application
Low pressure gas accelerated gene gun
OwnerHao-Jan Lin, Chien-Lung Cheninventors
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Abstract
The present invention relates to a gene gun and its application for genetic transformation, medical therapeutic or cosmetic purposes. Particular designs of the gene gun allow the biological materials to be delivered to the plant epidermal cellular tissues, the skin of an animal or human-being via a solution or a pre-mixed with the high pressure gas loading system. Moreover, the biological materials delivered by the gene gun are applied either in encapsulated nanoparticles or in the free form without using particle carriers.
Claims18
A low pressure gene gun, comprising:
- a gas source to provide a gas;
- a gene gun apparatus, wherein the gene gun apparatus comprises at least:
- a sprayer, wherein the sprayer includes a spray nozzle and a spray tube, and the spray nozzle comprises a front part and a back part, the front part of the spray nozzle is connected to the spray tube and the back part of the spray nozzle is connected to a connector, wherein an interior contour of the spray nozzle comprises a diverging part, a converging part and a spray neck positioned between the diverging part and the converging part;
- the connector connected to the back part of the spray nozzle and to the gas source through a valve, wherein the gas flows from the gas source and enters into the back part of the spray nozzle;
- a material delivery system connected to the sprayer, wherein the material delivery system comprises at least a container for storing a sample solution, wherein the container is connected to the spray neck of the sprayer through a channel and the sample solution is delivered to the sprayer through the channel and an outlet at the spray neck;
- a casing, enclosing at least the sprayer;
- and
- a trigger device disposed on the casing, for triggering and controlling a release of the gas, allowing the sample solution to be sprayed from the sprayer.
5 more elements
A low pressure gene gun, comprising:
- a container comprising a sample material pre-mixed with a high pressure gas;
- a connector, connected to the container through a valve;
- a sprayer, connected to the connector, wherein the sprayer includes a spray nozzle and a spray tube, and the spray nozzle comprises a front part and a back part, the front part of the spray nozzle is connected to the spray tube and the back part of the spray nozzle is connected to the container, wherein an interior contour of the spray nozzle comprises a diverging part, a converging part and a spray neck positioned between the diverging part and the converging part;
- a casing, enclosing the container and the sprayer;
- and
- a trigger device disposed on the casing, for triggering an open of the valve and controlling a release of the gas and the sample material, allowing the gas to flow through the sprayer and the sample material to be sprayed from the sprayer.
3 more elements
Dependencies are inferred from the claim text.