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US 2007/0163962 A1Published application
Fraction collection in high performance liquid chromatography
OwnerBrian Bidlingmeyer, Wesley Normaninventors
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Abstract
A system and method for substantially continuous fraction collection includes a control device and a fluidic switch. The control device selects the state of the fluidic switch, and thereby determines which of a plurality of output ports effluent will exit.
Claims25
A method of fraction collection comprising:
- providing a fluid stream including an analyte to a fluidic switch having a first output port and a second output port;
- providing a steering fluid to the fluidic switch, so as to selectively steer the analyte to a selected one of the first or second output ports;
- collecting the analyte from the selected output port in a first collection device;
- and
- moving a second collection device under the unselected output port of the switch during at least a portion of time during which the analyte is being collected.
2 more elements
A system for fraction collection, comprising:
- a fluidic switch having a first output port and a second output port, the fluidic switch being configured to receive a fluid stream from a liquid chromatography device via a fluid stream input port, wherein the fluidic switch may be controlled to be in a first state in which the fluid stream is steered to the first output port, or a second state in which the fluid stream is steered to the second output port;
- and
- a control device that determines the state of the fluidic switch, thereby determining whether the fluid stream exits the fluidic switch via the first output port or the second output port.
A system for fraction collection, comprising:
- a means for directing samples of substantially all of a fluid stream into a plurality of collection devices;
- and
- a means for directing the collection devices to the directing means, so that each collection device may be filled with a sample of the fluid stream.
Dependencies are inferred from the claim text.