Package and device for simultaneously maintaining low moisture and low oxygen levels
AssigneePfizer Inc.
InventorsDwayne Friesen, Kenneth Waterman
Life of this patent
Estimating the term…
Abstract
The present invention relates to a device for reducing the oxygen content of the air surrounding pharmaceutical dosage forms contained within an oxygen-permeable bottle, while also maintaining a relatively low moisture level in said air during the shelf-life of the product. Accordingly, a pharmaceutical package contains a dessicant in a first sub-container and a self-activated oxygen-absorber in a second sub-container.
Claims14
A pharmaceutical package comprising a bottle that maintains the oxygen content of the air within its interior volume at a reduced level relative to the oxygen content of the ambient air, comprising:
- A) said bottle,
- B) a desiccant disposed within a first sub-container disposed inside said bottle,
- said first sub-container being adapted to expose said dessicant to the interior of said bottle,
- C) a self-activated metal-based oxygen-absorber disposed within a second sub-container disposed inside said bottle,
- said absorber having sufficient oxygen-reducing capacity to reduce and to maintain the interior of said container at an oxygen level less than the oxygen level of the ambient air,
- said second sub-container having an orifice that exposes said absorber to the interior of said bottle, said orifice having dimensions that allow oxygen scavenging while limiting the diffusion rate of water from said second sub-container such that the interior of said container is maintained at a relative humidity less than 50%.
Dependencies are inferred from the claim text.