Packaging system with oxygen sensor for gas inflation/evacuation system and sealing system

A storable gas inflation/evacuation system and sealing system removably connectible to a proximal portion of a guidewire assembly which has an occlusive balloon at a distal portion thereof, including provision for indicating the presence of oxygen, comprising:

• a sealable container that isolates contents of the sealable container from ambient atmosphere when sealed;
• an oxygen-sensitive material located within the sealable container, the oxygen-sensitive material being inactive prior to exposure to radiation and activatable by exposure to radiation, the activation of the oxygen-sensitive material causing the oxygen-sensitive material to become sensitive to oxygen exposure only after activation and to remain sensitive to oxygen exposure after completion of radiation exposure and to undergo a visual change in response to such post-radiation oxygen exposure;
• a first syringe that selectively evacuates the guidewire assembly;
• a second syringe that selectively introduces a biocompatible gas into the guidewire assembly to inflate the occlusive balloon at the distal portion of the guidewire assembly a plurality of times;
• a sealing assembly removably connectible to the proximal portion of the guidewire assembly, the sealing assembly including a mechanism that selectively seals the proximal portion of the guidewire assembly at one of a plurality of separate locations to form one of a plurality of successive permanent airtight seals of the guidewire assembly;
• and,
• a valve arrangement that selectively opens and closes communication between the sealing assembly and the first syringe and between the sealing assembly and the second syringe.

A storable gas inflation/evacuation system and sealing system selectively operably connectible to and removable from a proximal portion of a guidewire assembly which has an occlusive balloon at a distal portion thereof, including provision for indicating the presence of oxygen, comprising:

• a sealable container that isolates contents of the sealable container from ambient atmosphere when sealed;
• an oxygen-sensitive material located within the sealable container, the oxygen-sensitive material being inactive prior to exposure to radiation and activatable by exposure to radiation, the activation of the oxygen-sensitive material causing the oxygen-sensitive material to become sensitive to oxygen exposure only after activation and to remain sensitive to oxygen exposure after completion of radiation exposure and to undergo a visual change in response to such post-radiation oxygen exposure;
• a handheld unit including a crimping mechanism having a first aperture and a sealing mechanism having a second aperture, there being a passageway extending from the first aperture to the second aperture for receiving the proximal portion of the guidewire assembly;
• a first syringe system that selectively evacuates the guidewire assembly;
• a second syringe system containing a volume of a biocompatible gas sufficient to inflate the occlusive balloon at the distal portion of the guidewire assembly a plurality of times;
• and,
• conduits operably connecting the first syringe system and the second syringe system to the second aperture of the handheld unit, the conduits including a valve arrangement that selectively connects only one of the first syringe system and the second syringe system to the second aperture at a time.

A storable gas inflation/evacuation system and sealing system removably connectible to a proximal portion of a guidewire assembly which has an occlusive balloon at a distal portion thereof, including provision for indicating the presence of oxygen, comprising:

• a sealable container that isolates contents of the sealable container from ambient atmosphere when sealed;
• an oxygen-sensitive material located within the sealable container, the oxygen-sensitive material being inactive prior to exposure to radiation and activatable by exposure to radiation, the activation of the oxygen-sensitive material causing the oxygen-sensitive material to become sensitive to oxygen exposure only after activation and to remain sensitive to oxygen exposure after completion of radiation exposure and to undergo a visual change in response to such post-radiation oxygen exposure;
• a handheld unit including a crimping mechanism having a first aperture and a sealing mechanism having a second aperture, there being a passageway extending from the first aperture to the second aperture for receiving the proximal portion of the guidewire assembly;
• an evacuating syringe that selectively evacuates the guidewire assembly;
• and,
• a plurality of inflation syringes, each inflation syringe containing a volume of a biocompatible gas sufficient to inflate the occlusive balloon at the distal portion of the guidewire assembly a single time.

A storable gas inflation/evacuation system and sealing system removably connectible to a proximal portion of a guidewire assembly which has an occlusive balloon at a distal portion thereof, including provision for indicating the presence of oxygen, comprising:

• a sealable container that isolates contents of the sealable container from ambient atmosphere when sealed;
• an oxygen-sensitive material located within the sealable container, the oxygen-sensitive material being inactive prior to exposure to radiation and activatable by exposure to radiation, the activation of the oxygen-sensitive material causing the oxygen-sensitive material to become sensitive to oxygen exposure only after activation and to remain sensitive to oxygen exposure after completion of radiation exposure and to undergo a visual change in response to such post-radiation oxygen exposure;
• a first syringe system that selectively evacuates the guidewire assembly;
• a second syringe system that selectively introduces a biocompatible gas into the guidewire assembly to inflate the occlusive balloon at the distal portion of the guidewire assembly a plurality of times;
• and,
• a plugging mechanism removably connectible to the proximal portion of the guidewire assembly that selectively seals the proximal portion of the guidewire assembly at one of a plurality of separate locations to form one of a plurality of successive permanent airtight seals of the guidewire assembly, including:
• a first aperture and a second aperture in fluid communication, the first aperture being capable of receiving therethrough the proximal portion of the guidewire assembly, and the second aperture being removably attachable to a conduit;
• an operational O-ring in coaxial alignment with the first aperture for operational engagement of the proximal portion of the guidewire assembly at a location proximal of the first aperture;
• a sealant O-ring in coaxial alignment with the first aperture and proximally spaced from the operational O-ring such that further insertion of the proximal portion of the guidewire assembly through the first aperture and past the operational O-ring will bring the proximal portion of the guidewire assembly into engagement with the sealant O-ring;
• and,
• a sealant confinement layer for receiving the proximal portion of the guidewire assembly some distance past the sealant O-ring, the sealant confinement layer confining sealant material such that insertion of the proximal portion of the guidewire assembly through the sealant confinement layer and into the sealant material forces the sealant material into the proximal portion of the guidewire assembly.