Chromatography cartridge and method for manufacturing a chromatography cartridge

A method of manufacturing a chromatography column, the method comprising:

• providing an elongated tubular housing having a first end and a second end, the first end integrally formed with the housing and including a port defining a fluid outlet, the tubular housing defining an interior space;
• positioning a first frit adjacent the first end in the interior space;
• filling the tubular housing with chromatography medium between the first frit and a second frit positioned adjacent the second end in the interior space;
• and
• spin-welding a cap to the tubular housing to close the second end, the cap including a port defining a fluid inlet, the cap including an exterior surface and a plurality of radially extending ribs on the exterior surface.

A method of manufacturing a chromatography cartridge, the method comprising:

• providing an elongated tubular housing having a substantially constant cross-section along its length, the tubular housing having an open first end;
• positioning a plug within the first end, the plug having a body portion and a shroud extending over the first end in a spaced-apart relationship with the body portion such that an inside surface of the tubular housing first end is in contact with the plug body portion and an outside surface of the tubular housing first end is in contact with the plug shroud;
• welding the inside surface of the tubular housing first end to the plug body portion and the outside surface of the tubular housing first end to the plug shroud;
• filling the tubular housing with a chromatography medium;
• and
• positioning a porous frit between the chromatography medium and the plug.