Therapeutically active dressings, their manufacture and use
AssigneeSanguibiotech AG
InventorsAlexander Teslenko, Boris Nikonow, Sergej Antonow
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Abstract
The invention relates to therapeutically active wound dressings based on polysaccharides, in particular chitosan, and protein, in particular collagen/gelatine, with improved properties, their manufacture, in particular the use of polycarbonic acids and polyfunctional amino acids, and their use, especially in the medical field.
Claims31
1-32. (canceled)
Wound dressing, wherein they display from 19 to 56% of one or more structural proteins, chosen from collagen, gelatine, derivatives or mixtures thereof, 18 to 58% of one or more structural polysaccharides, chosen from chitosan and (or) chitosan derivatives or mixtures thereof, 0.5 to 10% polycarbonic acids, 0.1 to 15% polyfunctional amino acids, 0 to 10% active substances, 0 to 30% excipients and/or additives, and 0.2 to 5% cross-linking agents.
Procedure for the production of a wound dressing, containing 19 to 56% of one or more structural proteins, chosen from collagen, gelatine, derivatives or mixtures thereof, 18 to 58% of one or more structural polysaccharides, chosen from chitosan and (or) chitosan derivatives or mixtures thereof, 0.5 to 10% polycarbonic acids, 0.1 to 15% polyfunctional amino acids, 0 to 10% active substances, 0.2 to 5% cross-linking agents, 0 to 30% excipients and/or additives, wherein to an aqueous solution of the polysaccharide a polycarbonic acid is added and to an aqueous solution of a structural protein is added the same or a different polycarbonic acid, subsequently both polymer solutions are dialyzed together and then polyfunctional amino acids and active substances, cross-linking agents, additives and excipients of the dialyzed reaction mixture are added if necessary.
Use of a wound dressing according to 33, for the accelerated healing of post-traumatic and surgical, infected, chronic wounds or burns.
Dependencies are inferred from the claim text.