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US 2007/0117769 A1Published application
Methods of modulating cell cycle and cell signaling pathways using biliverdin reductase
OwnerMahin Mainesinventor
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Abstract
The present invention relates to a method of modifying expression of cell cycle or cell signaling proteins. This method involves modifying the nuclear or cellular concentration of biliverdin reductase, or fragments or variants thereof, in a cell, whereby a change in the nuclear or cellular concentration of biliverdin reductase, or fragments or variants thereof, modifies the transcription or expression of cell cycle or cell signaling proteins.
Claims29
A method of modifying expression of cell cycle or cell signaling proteins comprising:
- modifying the nuclear or cellular concentration of biliverdin reductase, or fragments or variants thereof, in a cell, whereby a change in the nuclear or cellular concentration of biliverdin reductase, or fragments or variants thereof, modifies the transcription or expression of cell cycle or cell signaling proteins.
A DNA molecule encoding an siRNA that inhibits biliverdin reductase.
Dependencies are inferred from the claim text.