Articles including natural biodegradable polysaccharides and uses thereof
AssigneeSurModics, Inc.
InventorsStephen Chudzik, Dale Swan, Michael Burkstrand
Life of this patent
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Abstract
Medical articles having a body member including natural biodegradable polysaccharides are described. The body member is formed from a plurality of natural biodegradable polysaccharides having pendent coupling groups. The body member can also include a bioactive agent which can be released to provide a therapeutic effect to a patient.
Claims30
A medical implant comprising a biodegradable body member comprising a plurality of natural biodegradable polysaccharide associated via pendent coupling groups, wherein the biodegradable polysaccharide has a molecular weight of 500,000 Da or less.
A method for delivering a bioactive agent to a subject, the method comprising the steps of:
- providing a medical implant to a subject, the medical implant comprising a biodegradable body member comprising
- a plurality of natural biodegradable polysaccharide associated via pendent coupling groups, wherein the biodegradable polysaccharide has a molecular weight of 500,000 Da or less, and
- bioactive agent;
- and
- exposing the medical implant to a carbohydrase to promote the degradation of the medical implant and release of the bioactive agent, wherein there is substantially no release of the bioactive agent in the absence of the carbohydrase.
Dependencies are inferred from the claim text.