Purified trimeric S protein as vaccine against severe acute respiratory syndrome virus infections
OwnerYiu Kam, Francois Kien +3inventors
InventorsYiu Kam, Francois Kien, Kid Chu, Anjeanette Roberts, Kanta Subbarao
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Abstract
Immunogenic compositions and vaccines associated with the Spike protein of SARS Corona Virus (SARS CoV) are disclosed.
Claims8
An immunogenic composition comprising at least one recombinant SARS CoV Spike protein having all of the epitopes of native Spike protein and free of other native SARS CoV components in an amount sufficient to induce an immunogenic or protecting response in vivo, and a pharmaceutically acceptable carrier therefor.
A method of vaccinating against SARS CoV comprising administering any combination of the nucleic acid encoding Spike polypeptides, the proteins and polypeptides to an individual.
Dependencies are inferred from the claim text.