Bioreactor for growing engineered tissue
OwnerRobert Moreinventor
Life of this patent
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Abstract
A bioreactor and a method for growing engineered tissue provide facing surfaces in a vessel for containing cell-culture media. The facing surfaces are equidistant and define a gap therebetween while providing substrates for cell tissue growth. By maintaining conditions within the vessel conducive to cell tissue growth and moving the surfaces relative to one another within such cell culture media, tissue growing thereupon is subjected to physiological flow and shear stress, preferably through the use of oscillating motion, and engineered tissue is produced.
Claims18
A bioreactor for growing engineered tissue, which bioreactor comprises:
- a vessel for containing cell-culture media,
- a pair of approximately parallel surfaces which define a uniform gap therebetween, said surfaces providing substrates upon which cell tissue growth may occur within such gap,
- means for maintaining conditions within said vessel conducive to cell tissue growth, and
- means for moving said surfaces relative to one another within media supplied to said vessel so as to subject cell tissue growing upon and between said surfaces to physiological flow and to shear stress.
A method for growing engineered tissue, which method comprises:
- providing facing surfaces in a bioreactor vessel,
- supplying said vessel with cell-culture media under conditions conducive to cell tissue growth, and
- maintaining relative movement between said facing surfaces so as to subject cell tissue growing upon said surfaces to physiological flow and to shear stress.
Dependencies are inferred from the claim text.