Adaptive resynchronization therapy system
AssigneeAi-Semi Ltd
InventorRami Rom
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Abstract
A system including a learning module and an algorithmic module for learning a physiological aspect of a patient body and regulating the delivery of a physiological agent to the body. An embodiment of the invention is an adaptive CRT device performing biventricular pacing in which the AV delay and VV interval parameters are changed dynamically according to the information supplied by the IEGM, hemodynamic sensor and online processed data, in order to achieve optimal hemodynamic performance. A learning module, preferably using artificial neural network, performs the adaptive part of the algorithm supervised by an algorithmic deterministic module, internally or externally from the implanted pacemaker or defibrillator.
Claims15
An adaptive feed-back controlled system for regulating a physiological function of a body, comprising:
- at least one sensor for continuously monitoring a significant physiological performance;
- a learning neural network module for receiving and processing information of said at least one sensor and for learning at least one physiological aspect of said body;
- a deterministic algorithmic module receiving parameters from said neural network module and for supervising online said learning module, and
- a therapeutic delivering means connected to said deterministic algorithmic module and wherein said.
A method for regulating a controlled delivery of a physiologically active agent to a patient comprising the steps of:
- obtaining continuous signal from at least one sensor monitoring said patient;
- processing said continuous signal by an algorithmic processing module and a learning module, and wherein said learning modules carries out adaptive learning in connection with said at least one sensor is first supervised by applying an accepted set of parameters, and
- affecting a delivery module in accordance with said processing, wherein said affect either results from said algorithmic process or from said learning processing.
A method for adaptive biventricular pacing control comprising the steps of:
- programming initial AV (atriaventricular) delay parameter and VV (interventricular delay) interval parameter of an algorithmic module;
- operating in normal CRT mode wherein an algorithmic deterministic module for controlling delivery of pulses, wherein pacing is carried out according to said parameters and wherein learning operation with said parameters takes place, and
- transition to adaptive CRT mode wherein said AV delay and VV interval change dynamically in order to achieve optimal hemodynamic performance, and wherein said adaptive mode is limited to perform in a predefined low limit of hemodynamic performance.
Dependencies are inferred from the claim text.