Temperature-responsive hydrogel
AssigneeTeijin Limited
InventorsEiichi Kitazono, Hiroaki Kaneko
Life of this patent
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Abstract
A compound made of a hyaluronic acid having from 300 to 30,000 repeating units and a polyalkylene oxide derivative having a specific structure and a specific molecular weight, wherein the content of the polyalkylene oxide derivative is from 5 to 100 equivalents per 100 equivalents of the carboxyl group of the hyaluronic acid; and a hydrogel containing the subject compound.
Claims2
A compound comprising a hyaluronic acid and a polyalkylene oxide derivative, represented by the following general formula (1), wherein the content of the polyalkylene oxide derivative residue in R1 is from 5 to 100 equivalents per 100 equivalents of the carboxyl group of the hyaluronic acid:
- (wherein R2 represents NH or O;
- R3 represents H or CH3;
- R4 represents C2H4 or CH2CH (CH3);
- R5 represents any one of H, CH3, C2H5, and C4H9;
- l represents an integer of from 300 to 30,000;
- and m represents an integer of from 3 to 140.)
Dependencies are inferred from the claim text.