Insulin secretion potentiator
AssigneeUse-Techno Corporation
InventorsFutoshi Matsuyama, Yutaka Seino, Mitsuo Fukushima, Toshihiro Miura, Takeshi Fujita, Tetsuo Kaneko
Life of this patent
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Abstract
The present invention provides early insulin secretion stimulators consisting of triterpenes represented by the following general formula (1) and/or triterpenes represented by the following general formula (2). [where R1 represents COOH, etc., R11 and R12 represent CH2OH, etc., X1 represents hydrogen or OH and X11, X12, X21 and X22 represent OH, etc.]
Claims21
1-10. (canceled)
A method for decreasing blood glucose levels in a mammal in need thereof, comprising administering to the mammal an effective amount of a triterpene represented by the following general formula (1) or (2)
- wherein
- R1 represents COOH, CHO, CH3 or CH2OH;
- R11 and R12 each independently represent CH3, CH2OH or COOH;
- X1 represents hydrogen or OH;
- and
- X11, X12, X21 and X22 each independently represent hydrogen, OH, O-ether, O-ester or acyl, with the proviso that
- two among X11, X12, X21 and X22 are hydrogen and the other two are OH or acyl,
- X11 and X12 are not simultaneously OH or acyl, and
- X11 and X12 or X21 and X22 may together form an ═O group.
A method for increasing blood insulin levels in a mammal in need thereof, comprising administering to the mammal an effective amount of a triterpene represented by the following general formula (1) or (2)
- wherein
- R1 represents COOH, CHO, CH3 or CH2OH,
- R11 and R12 each independently represent CH3, CH2OH or COOH,
- X1 represents hydrogen or OH, and
- X11, X12, X21 and X22 each independently represent hydrogen, OH, O-ether, O-ester or acyl,
- with the proviso that
- two among X11, X12, X21 and X22 are hydrogen and the other two are OH or acyl,
- X11 and X12 are not simultaneously OH or acyl, and
- X11 and X12 or X21 and X22 may together form an ═O group.
Dependencies are inferred from the claim text.