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US 2006/0235032 A1Published application
Substituted quinazolines as antiviral agents, especially against cytomegaloviruses
AssigneeBayer Schering Pharma Aktiengesellschaft
InventorsTobias Wunberg, Judith Baumeister, Mario Jeske, Susanne Nikolic, Frank Submeier, Holger Zimmermann, Rolf Grosser, Kerstin Henninger, Guy Hewlett, Jorg Keldenich, Dieter Lang, Tse-I Lin
Life of this patent
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Abstract
The invention relates to substituted quinazolines and to methods for the production thereof, in addition to the use thereof in the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, especially against cytomegaloviruses.
Claims17
A compound of the formula
- in which
- R1, R2 and R3 are independently of one another hydrogen, alkyl, alkoxy, carboxyl, alkylcarbonyl, alkoxycarbonyl, aminocarbonyl, trifluoromethyl, halogen, cyano, hydroxy or nitro,
- R4 and R5 are independently of one another hydrogen, alkyl, alkoxy, cyano, halogen, nitro, trifluoromethyl or trifluoromethoxy,
- R6 is alkyl, cyano, halogen, nitro or trifluoromethyl,
- R7 and R8 are independently of one another hydrogen, halogen, alkyl or alkoxy, and
- R9 is aryl or 1,3-benzodioxol-5-yl in which aryl and 1,3-benzodioxol-5-yl may be substituted by 1 to 3 substituents, where the substituents are selected independently of one another from the group consisting of alkoxy, alkylthio, carboxyl, alkylcarbonyl, alkoxycarbonyl, aminocarbonyl, trifluoromethyl, halogen, carbamoyl, cyano, hydroxy, amino, alkylamino, nitro and optionally hydroxy-substituted alkyl,
- or one of its salts, its solvates or the solvates of its salts.
4 more elements
(canceled)
(canceled)
(canceled)
Dependencies are inferred from the claim text.