Compositions and methods for reducing the risk of epileptic occurrence and/or for treatment of seizure disorders

A pharmaceutical composition comprising a therapeutically effective amount of the compound of the general formula (I)

• and a pharmaceutically acceptable carrier or excipient, wherein R′ represents an anti-epileptic drug, anticonvulsive drug, neuroprotective drug, neurotransmitter or nootrope moiety;
• and
• R is selected from the group consisting of —CH2OH, —CHO and —CH2NH2;
• and pharmaceutically acceptable salts thereof.

A method of treatment of a neurological disease or disorder comprising administering to an individual in need thereof a therapeutically effective amount of a compound of the general formula (I):

• wherein R′ represents an anti-epileptic drug, anticonvulsive drug, neuroprotective drug, neurotransmitter or nootrope moiety;
• and
• R is selected from the group consisting of —CH2OH, —CHO and —CH2NH2;
• and pharmaceutically acceptable salts thereof.

A method for preventing epileptic episodes, alleviating epileptic episodes and/or reducing side effects of anti-epileptic drugs comprising the step of administering to a subject a therapeutically effective amount of a compound of the general formula (I):

• wherein R′ represents an anti-epileptic drug, anticonvulsive drug, neuroprotective drug neurotransmitter or nootrope moiety;
• and
• R is selected from the group consisting of —CH2OH, —CHO and —CH2NH2;
• and pharmaceutically acceptable salts thereof.