Expression of soluble, active eukaryotic glycosyltransferases in prokaryotic organisms

A method of producing a soluble active eukaryotic glycosyltransferase in a prokaryotic microorganism, wherein the prokaryotic microorganism has an oxidizing environment,

• the method comprising the steps of
• a) expressing a nucleic acid that encodes the eukaryotic glycosyltransferase in the prokaryotic microorganism;
• and
• b) growing the microorganism under conditions that allow expression of the soluble active eukaryotic glycosyltransferase within a cellular compartment of prokaryotic microorganism.