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US 2006/0234306 A1Published application
Assay method
AssigneeGenentech, Inc.
InventorsDean Artis, David Jackson, Susan Keating, Maureen Beresini
Life of this patent
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Abstract
A new method for assaying the ability of a compound to block the binding of an α4 integrin to a binding partner thereof provides a useful screening tool.
Claims11
A method of detecting an inhibitor of the binding of an α4 integrin to a binding partner thereof, comprising
- combining (a) a labeled peptide capable of binding an α4 integrin and (b) a sample to be tested, with an isolated α4 integrin under conditions suitable for binding of the isolated α4 integrin to the labeled peptide, and
- detecting or measuring the amount of sample bound to the isolated α4 integrin.
Dependencies are inferred from the claim text.