Novel proteins and nucleic acids encoding same

Abstract

The present invention provides novel isolated polynucleotides and small molecule target proteins encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target protein or any derivative, variant, mutant or fragment of that protein, polynucleotide or antibody are disclosed, as are methods in which the small molecule target protein, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Dependencies are inferred from the claim text.