Microarrays displaying encoded molecules
AssigneeNuevolution A/S
InventorsPer-Ola Freskgard, Henrik Pedersen
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Abstract
Disclosed is a microarray comprising a plurality of single stranded nucleic acid probes immobilized in discrete areas of a solid support, said probes being hybridised to a library of complexes, wherein each complex comprises an encoded molecule and a template which codes for said molecule, said template comprising a number of codons which codes for chemical entities which upon reaction form a reaction product which at least partly form part of the encoded molecule.
Claims21
A microarray comprising a plurality of single stranded nucleic acid probes immobilized in discrete areas of a solid support, said probes being hybridised to a library of complexes, wherein each complex comprises an encoded molecule and a template which codes for said molecule, said template comprising a number of codons which codes for chemical entities which upon reaction form a reaction product which at least partly form part of the encoded molecule.
A method for preparing a microarray displaying a library of encoded molecules, wherein an oligonucleotide microarray comprising a plurality of single stranded nucleic acid probes immobilized in discrete areas of a solid support is mixed under conditions which allows for specific hybridisation with a library of complexes, each of said complexes comprising an encoded molecule and a template which codes for said molecule, said template comprising a number of codons which codes for chemical entities which upon reaction form a reaction product which at least partly form part of the encoded molecule.
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Dependencies are inferred from the claim text.