Modified release dosage form
AssigneeMcNeil-PPC, Inc.
InventorHarry Sowden
Life of this patent
Estimating the term…
Abstract
The present invention relates to a medicinal dosage form having a first core, a second core, and a shell that surrounds a first portion of each core and a fill material that covers a second portion of at least one core, wherein the fill material that is provided over at least one core is not in contact with any portion of the other core. e. The inventive dosage forms provide modified release of one or more active ingredients contained therein. The present invention also relates to methods for manufacturing such medicinal dosage forms.
Claims30
A medicinal dosage form comprising a first core, a second core, and a shell that is provided over and having a surface conforming or defining a first portion of each core and a fill material that is provided over and having a surface conforming to or defining a second portion of at least one core, wherein the fill material that is provided over at least one core is not in contact with any portion of the other core.
A medicinal dosage form comprising at least one core containing a pharmaceutical active ingredient and having a cavity, at least one shell portion that is provided over and having a surface conforming or defining a first portion of the at least one core and at least one fuse material that is provided in the cavity of the at least one core, wherein the initial release of pharmaceutical active from the core is governed by the dissolution or erosion profile of the fuse material.
A medicinal dosage form comprising at least one core containing a pharmaceutical active ingredient, a unitary shell portion that is provided over and is having a surface conforming or defining a first portion of the at least one core and a molding plug that is provided in the cavity of the at least one core, wherein the molding plug does not contain any pharmaceutical active ingredient.
A medicinal dosage form comprising at least two cores, at least one shell portion that is provided over and having a surface conforming or defining a first portion of the cores and at least one fuse material that is provided between and in contact with at least two cores of the dosage form.
Dependencies are inferred from the claim text.