Controlled released dosage forms
AssigneeTeva Pharmaceutical Industries Ltd.
InventorsE. Lerner, Vered Rosenberger, Ofer Aqua, Moshe Flashner-Barak
Life of this patent
Estimating the term…
Abstract
A zero-order release pharmaceutical dosage form for oral administration to a patient comprising a core tablet sheathed in an annular body of compressed powder or granular material is provided. A preferred embodiment of the zero-order release pharmaceutical dosage form is a solid pharmaceutical dosage form which reduces contact of the active ingredient in solid form with the mucosa lining the gastrointestinal tract, which is particularly advantageous for delivering an ulcerative drug. A process for making the zero-order release pharmaceutical dosage form are also provided.
Claims11
A pharmaceutical dosage form for oral administration to a patient comprising a core tablet sheathed in a annular body of compressed powder or compressed granular material, wherein an active ingredient is included in at least one of the core tablet or the annular body, wherein the active ingredient is released from the dosage form at a rate from 3% per hour to 12% per hour over a period of seven hours or more.
The pharmaceutical dosage form of claim 11 wherein the carbidopa is completely release within about one hour after the dosage form contacts water.
Dependencies are inferred from the claim text.