Matrix composed of a naturally-occurring protein backbone cross linked by a synthetic polymer and methods of generating and using same
AssigneeRegentis Biomaterials Ltd.
InventorsDror Seliktar, Liora Almany
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Abstract
A method of treating a disorder characterized by tissue damage is provided. The method comprising providing to a subject in need-thereof a composition which comprises a synthetic polymer attached to denatured fibrinogen or a therapeutic portion of the fibrinogen, the composition being formulated for releasing the therapeutic portion of the fibrinogen in a pharmacokinetically regulated manner, thereby treating the disorder characterized by tissue damage or malformation.
Claims58
A composition-of-matter comprising a synthetic polymer attached to denatured fibrinogen or a therapeutic portion of said denatured fibrinogen.
A hydrogel comprising a composition-of-matter which comprises a synthetic polymer attached to denatured fibrinogen or a therapeutic portion of said denatured fibrinogen.
A medical device comprising a composition-of-matter which comprises a synthetic polymer attached to denatured fibrinogen or a therapeutic portion of said denatured fibrinogen.
A pharmaceutical composition comprising a composition-of-matter which comprises a synthetic polymer attached to denatured fibrinogen or a therapeutic portion of said denatured fibrinogen.
A method of treating a disorder characterized by a tissue damage, the method comprising providing to a subject in need-thereof a composition which comprises a synthetic polymer attached to denatured fibrinogen or a therapeutic portion of said fibrinogen, said composition being formulated for releasing said therapeutic portion of said fibrinogen in a pharmacokinetically regulated manner, thereby treating the disorder characterized by tissue damage or malformation.
Dependencies are inferred from the claim text.