Bone Growth Compositions and Methods
AssigneeNeuropro Technologies, Inc.
InventorsBenjamin Remington, David Bearss, Kavian Shahi
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Abstract
The present invention provides an improved technique for spinal fusion involving the administration of an HMG-CoA reductase inhibitor to a fusion. The HMG-CoA reductase inhibitor is preferably delivered to the site by a carrier. More preferably, the HMG-CoA reductase inhibitor is delivered to the site by a non-compressible delivery vehicle. The invention is suitable for promoting non-anatomic or heterotopic bone growth between any bony surfaces where bone growth is desired but does not naturally occur.
Claims22
A method for enhancing non-anatomic bone formation of a foot or ankle bone, said method comprising administering an HMG-CoA reductase inhibitor to said foot or ankle bone.
A carrier for enhancing bone formation wherein said carrier comprises an HMG-CoA reductase inhibitor and an antibiotic, an antioxidant, an anti-inflammatory, a growth factor, an immunosuppressant or an analgesic.
A method for treating a failed arthroplasty comprising promoting arthrodesis comprising administering an HMG-CoA reductase inhibitor to a malformed or degenerated joint.
Dependencies are inferred from the claim text.