Vaccines
OwnerTuen-Yee Wong, Anthony So +1inventors
InventorsTuen-Yee Wong, Anthony So, Thomas Ko
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Abstract
Processes for the production of a stabilised vaccine composition of labile immunogens, wherein a fluid comprising one or more immunogens is sprayed into a reactor containing fluidised particles of a pharmaceutically acceptable water soluble material at a temperature of about 25° C. to about 50° C., such that the immunogen coats and is dried onto the particles under the fluidising conditions, and thereafter collecting from said reactor dried immunogen containing particles having a moisture content between about 0.1% w/w to about 10% w/w are described. Also described are stabilised vaccine compositions of labile immunogens.
Claims42
A process for the production of a vaccine composition of labile immunogens, wherein a fluid comprising one or more immunogens is sprayed into a reactor containing fluidized particles of a pharmaceutically acceptable water soluble material at a temperature of about 25° C. to about 50° C., such that the immunogen coats and is dried onto the particles under the fluidizing conditions, and thereafter collecting from said reactor dried immunogen containing particles having a moisture content between about 0.1% w/w to about 10% w/w so as to give a stabilized vaccine composition.
A stabilized vaccine composition comprising immunogen coated particles of a pharmaceutically acceptable water soluble material, the composition having a moisture content between about 0.1% w/w to about 10% w/w.
Dependencies are inferred from the claim text.