Compositions and methods of therapy
OwnerRodney Kellyinventor
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Abstract
A method of inducing tolerance to an antigen in a patient, the method comprising administering to the patient an agent which raises the effective cAMP concentration in a monocyte cell and GMCSF or a derivative thereof. Preferably, the agent which raises the effective cAMP concentration in a monocyte cell is a prostaglandin or agonist thereof which stimulates cAMP production in a monocyte. Optionally, the antigen to which it is desired to induce tolerance, or a derivative thereof, may also be administered.
Claims62
A method of inducing tolerance to an antigen in a patient, the method comprising administering to the patient an agent which raises the effective cAMP concentration in a monocyte cell and granulocyte-macrophage colony stimulating factor (GMCSF) or a derivative thereof.
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17-19. (canceled)
A composition comprising an agent which raises the effective cAMP concentration in a monocyte cell and granulocyte-macrophage colony stimulating factor (GMCSF) or a derivative thereof.
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52-65. (canceled)
A therapeutic system for inducing tolerance to an antigen in a patient, the system comprising an agent which raises the effective cAMP concentration in a monocyte cell and GMCSF or a derivative thereof.
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Dependencies are inferred from the claim text.