Antibacterial 5,5'-disubstituted 3,3'-dialkoxy-2,2'-dihydroxy-1,1'-biphenyl compounds and related methods
OwnerRavi Subramanyaminventor
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Abstract
The invention provides an antiplaque oral composition that includes an orally acceptable carrier; and an antibacterially effective amount of a compound of structure (I) In the structure, R1 and R2 are independently selected from a lower C1-4 alkyl group and R3 and R4 are independently an alkenyl or alkyl group having from 1 to 20 carbon atoms. Also included in the invention are toothpastes or tooth gels that include at least one humectant; at least one abrasive compound; and an antibacterially effective amount of the compound represented by the structure of formula (I). Also provided are methods of inhibiting bacterial growth in the oral cavity of an animal by application of the compound of formula (I).
Claims31
An antiplaque oral composition comprising
- an orally acceptable carrier;
- and
- an antibacterially effective amount of a compound of structure (I)
- wherein R1 and R2 are independently a lower C1-4 alkyl group and R3 and R4 are independently an alkenyl or alkyl group having from 1 to 20 carbon atoms.
A toothpaste or gel composition comprising
- at least one humectant;
- at least one abrasive compound;
- and
- an antibacterially effective amount of
- wherein R1 and R2 are independently a lower C1-4 alkyl group and R3 and R4 are independently an alkenyl or alkyl group having from 1 to 20 carbon atoms.
A method for inhibiting bacterial growth in the oral cavity of an animal, comprising applying to the oral surfaces of the subject animal an antibacterial composition comprising a compound of structure (I)
- wherein R1 and R2 are independently a lower C1-4 alkyl group and R3 and R4 are independently an alkenyl or alkyl group having from 1 to 20 carbon atoms.
Dependencies are inferred from the claim text.