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US 2006/0233713 A1Published application
Gadolinium particle-based MRI contrast agents
AssigneeSRI International
InventorDavid MacQueen
Life of this patent
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Abstract
Compositions comprising purified gadolinium-exchanged carboxylate-alumoxane nanoparticles in an aqueous solution are provided for use as MRI contrast agents. Targeted imaging is provided by nanoparticles comprising surface-bound antibodies specific for biomolecules present in a patient.
Claims20
A composition comprising purified gadolinium-exchanged carboxylate-alumoxane nanoparticles in an aqueous solution.
A composition comprising a gadolinium chelate linked to a nanoparticle, wherein the nanoparticle is a boehmite nanoparticle or a carboxylate-alumoxane nanoparticle.
Dependencies are inferred from the claim text.