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US 2006/0224529 A1Published application
Artificial intelligence and global normalization methods for genotyping
AssigneeIllumina, Inc.
InventorBahram Kermani
Life of this patent
Estimating the term…
Abstract
Described herein are systems and methods for normalizing data without the use of external controls. Also described herein are systems and methods for analyzing cluster data, such as genotyping data, using an artificial neural network.
Claims19
1-29. (canceled)
A method of clustering genetic data for n loci, wherein n is an integer greater than one, comprising
- (a) obtaining genetic data comprising n sets of first and second signal values related in a coordinate system, wherein said first and second signal values are indicative of the levels of a first and second allele, respectively, at n loci;
- (b) comparing fit of said genetic data to each of a plurality of cluster models using an artificial neural network, thereby determining a best fit cluster model;
- and
- (c) assigning said signal values to at least one cluster according to said best fit cluster model.
1 more element
47-48. (canceled)
Dependencies are inferred from the claim text.