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US 2006/0223786 A1Published application
Transdermal pain control method and device
OwnerDavid Smith, Mark Badria +1inventors
InventorsDavid Smith, Mark Badria, Ollen Williams
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Abstract
Compositions comprising skin-permeable pharmaceutically effective amounts of an opioid agonist; an N-methyl-D-aspartate receptor antagonist and an anti-inflammatory may be incorporated into formulations and devices suitable for transdermal delivery of the active ingredients to alleviate pain.
Claims20
A composition comprising pharmaceutically effective amounts of
- (a) an opioid agonist;
- (b) an N-methyl-D-aspartate receptor antagonist different from the opioid agonist;
- and
- (c) an anti-inflammatory, the anti-inflammatory being different from the opioid agonist and different from the N-methyl-D-aspartate receptor antagonist;
- wherein the opioid agonist, the N-methyl-D-aspartate receptor antagonist and the anti-inflammatory are each in a skin-permeable form;
- and
- wherein the composition is free of a pharmaceutically effective amount of an α3β4 nicotinic receptor antagonist.
4 more elements
Dependencies are inferred from the claim text.