Biosensor system that enables spectral multiplexing

A method for characterizing the binding of biological molecules comprising:

• applying a capture agent to first and second sensors, wherein the first and second sensors have different resonant frequencies;
• exposing the first and second sensors to an analyte;
• applying an optical signal to the first and second sensors in parallel;
• and
• detecting the optical signal after it has interacted with the first and second sensors.

A biosensor system comprising:

• a substrate;
• a first sensor fabricated on the substrate, the first sensor having a first resonant frequency;
• and
• a second sensor fabricated on the substrate, the second sensor having a second resonant frequency, wherein the first resonant frequency is different from second resonant frequency;
• and
• a spectral multiplexing system in optical communication with the first and second sensors, the spectral multiplexing system having an optical source configured to output an optical signal, a signal distribution system configured to provide the optical signal to the first and second sensors in parallel, and a detector configured to detect portions of the optical signal that interact with the first and second sensors.