Temozolomide storage system
AssigneeChemagis Ltd.
InventorsOleg Braverman, Rimma Feinshtein, Alex Weisman, Joseph Kaspi
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Abstract
The present invention provides an improved storage system for temozolomide, which preferably includes one or more bags (e.g., 3 bags, optionally containing a desiccant interposed between two of the bags). The storage system of the present invention can maintain temozolomide as a white, stable, and dry material after long periods of storage. The present invention also provides methods of producing and storing temozolomide as a stable, white solid.
Claims25
A storage system comprising a container and temozolomide contained therein as a white solid, wherein the storage system is capable of providing an internal environment having a substantially lower humidity level, a substantially lower oxygen level, a substantially lower light level, or a combination thereof, relative to the environment outside of the storage system.
A method for maintaining temozolomide as a white solid for long storage periods, the method comprising packaging temozolomide as a white solid within a controlled environment having reduced humidity level, low oxygen atmosphere, low light level, or a combination thereof, relative to the external environment.
A process for producing temozolomide as a white solid, the process comprising synthesizing temozolomide in an inert atmosphere.
Dependencies are inferred from the claim text.