System and method for loading a beneficial agent into holes in a medical device
AssigneeConor Medsystems, Inc.
InventorsStephen Diaz, Theodore Parker
Life of this patent
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Abstract
A system for loading a beneficial agent into holes in a medical device includes a punch system for punching plugs of beneficial agent from a thin sheet into the holes in the medical device. The loading of a beneficial agent in the form of a thin film allows the formation of multilayered structures within the holes to control release kinetics and prevent any meniscus which occurs when a beneficial agent is deposited as a liquid in the holes and dried. The punch type loading system also can provide the ability to deliver large and potentially sensitive molecules including proteins, enzymes, antibodies, antisense, ribozymes, gene/vector constructs, and cells including endothelial cells.
Claims16
A method for loading a medical device with a beneficial agent, the method comprising:
- providing a medical device with an exterior surface and a plurality of holes intersecting the exterior surface;
- providing a film of a beneficial agent;
- and
- pressing plugs of the film into the holes in the medical device.
A system for loading a medical device with a beneficial agent, the system comprising:
- a holder for supporting a medical device having a plurality of holes for receiving a beneficial agent;
- a film of a beneficial agent;
- and
- at least one punch configured to press plugs of the film into the holes in the medical device.
Dependencies are inferred from the claim text.