Particles containing an acitve agent in the form of a co-precipitate
OwnerGerard Cousin, Gael Lamoureuxinventors
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Abstract
The invention relates to particles containing an active agent in the form of a co-precipitate, to a method for producing said particles and to pharmaceutical forms containing said particles.
Claims17
A process for the preparation of a particle composed of a coprecipitate applied as a layer around a neutral hydrophilic carrier by spraying an organic solution over said neutral hydrophilic carrier, said solution comprising at least one active substance, one surface-active agent and one hydrophilic polymer, wherein the spraying of the whole of the solution is carried out in at least two separate stages, each of these stages being followed systematically by a stage of milling the product obtained on conclusion of the preceding stage.
A particle composed of a coprecipitate which is applied as a layer around a carrier and which comprises at least one active substance, one surface-active agent and one hydrophilic polymer, wherein it is capable of being obtained by spraying a solution comprising at least one active substance, one surface-active agent and one hydrophilic polymer, said spraying being carried out at least in two separate stages, said stages each being followed by a milling stage.
Dependencies are inferred from the claim text.