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US 2006/0222712 A1Published application
Acne gel
AssigneeConnetics Corporation
InventorsLincoln Krochmal, Alex Yaroshinsky
Life of this patent
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Abstract
This combination of clindamycin (1%) and tretinoin (0.025%), solubilized in a hydrogel, resulted in significantly greater improvements in acne vulgaris (reduced lesion counts and ISGA) than either drug alone or vehicle and effectively treated both non-inflammatory and inflammatory lesions with a convenient, once-daily application.
Claims21
A method for treating non-inflammatory lesions of acne vulgaris, said method comprising:
- administering a composition comprising clindamycin or a pharmaceutically acceptable salt or a prodrug thereof to a subject, to treat said non-inflammatory lesions.
A method for treating inflammatory lesions of acne vulgaris, said method comprising:
- administering a composition comprising tretinoin to a subject, to treat said inflammatory lesions.
A method for treating acne vulgaris, said method comprising:
- administering a composition comprising a combination of active agents comprising clindamycin and tretinoin to a subject, wherein the median time to 50% reduction of total lesion count is shorter than for either active agent alone.
Dependencies are inferred from the claim text.