Stable immunoprophylactic and therapeutic compositions derived from transgenic plant cells and methods for production
AssigneeDow AgroSciences LLC
InventorsTimothy Miller, Matthew Fanton, Steven Webb
Life of this patent
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Abstract
The present invention generally relates to the field of immunology and provides immunoprotective compositions and methods for preparing such compositions from transgenic plant cells. The present invention also relates to the field of protein production (e.g., the recombinant production of enzymes, toxins, cell receptors, ligands, signal transducing agents, cytokines, or other proteins expressed in trangenic plant cell culture) and provides compositions comprising these proteins.
Claims8
A composition comprising an immunoprotective particle or a biologically active protein particle in admixture with one or more pharmaceutically-acceptable adjuvants, diluents, carriers, or excipients, wherein either of said particles is produced from a transgenic plant and comprises a heterogeneous particle or aggregate composed of the recombinant immunoprotective antigen or the recombinant biologically active protein and protein, lipid, carbohydrate, nucleic acid or combinations thereof from said transgenic plant.
A method for vaccinating or immunizing an animal comprising administering to an animal or human a dose of a composition in an amount sufficient to vaccinate, immunize, stimulate an immune response, stimulate the production of specific antibodies, or stimulate a cellular immune response of said animal, wherein said composition comprises an immunoprotective particle or a biologically active protein particle in admixture with one or more pharmaceutically-acceptable adjuvants, diluents, carriers, or excipients, wherein either of said particles is produced from a transgenic plant and comprises a heterogeneous particle or aggregate composed of the recombinant immunoprotective antigen or the recombinant biologically active protein and protein, lipid, carbohydrate, nucleic acid or combinations thereof from said transgenic plant.
Dependencies are inferred from the claim text.