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US 2006/0222655 A1Published application
Compositions and methods for preventing and treating endotoxin-related diseases and conditions
OwnerJames McShaneinventor
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Abstract
The invention provides pharmaceutical compositions for preventing and treating endotoxin-related diseases and conditions, as well as methods for making and using such compositions.
Claims22
A composition comprising a compound having the formula:
- pharmaceutically acceptable salt thereof, and an antioxidant.
A method of making a pharmaceutical composition comprising an antiendotoxin compound, said method comprising admixing said compound and an antioxidant.
A method of making a pharmaceutical composition comprising an antiendotoxin compound, said method comprising the steps of:
- (i) dissolving said antiendotoxin compound in an aqueous solution of sodium hydroxide;
- (ii) adding a disaccharide stabilizer to said solution;
- (iii) adding an antioxidant to said solution;
- (iv) lowering the pH of said solution;
- (v) filter sterilizing said solution;
- and
- (vi) freeze-drying said solution.
4 more elements
Dependencies are inferred from the claim text.