Antibodies operably linked to selected chemoattractants
AssigneeXencor, Inc.
InventorsKenton Abel, Arthur Chirino, Omid Vafa
Life of this patent
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Abstract
An antibody or fragment thereof operably linked to a one or more chemoattractants selected from the group consisting of: C5a or fragments thereof; C3a or fragments thereof; C4a or fragments thereof; and, formyl-Met-Leu-Phe (fMLP).
Claims15
A chemoattractant-antibody conjugate comprising an antibody operably linked to a chemoattractant or fragment thereof, the chemoattractant selected from the group consisting of C5a, C4a, and C3a.
The chemoattractant-antibody conjugate of claim 16 wherein said chemoattractant is operably linked by a glycine-serine linker.
The chemoattractant-antibody conjugate of claim 16 wherein said chemoattractant is directly connected to the C-terminal amino acid of an antibody heavy chain.
Dependencies are inferred from the claim text.