Composition for treating dry eye and related methods of manufacture and methods of use
AssigneeBausch & Lomb Incorporated
InventorsErning Xia, Joseph Salamone, X. Liu
Life of this patent
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Abstract
The present invention is directed to a composition for treating dry eye comprising, in one embodiment, carboxymethylcellulose and a polyol. Such compositions have been found to alleviate the symptoms of dry eye and remain in the eye for a long period of time.
Claims57
A dry eye composition comprising an aqueous solution of carboxy-containing polymer and a polyol wherein the carboxy-containing polymer has a molecular weight that is a minimum of about 90 kDa and a maximum of about 700 kDa and has a Mark-Houwink constant that is a minimum of about 0.6 and a maximum of about 1.5.
A method of treating dry eye comprising administering to an eye a composition comprising an aqueous solution of carboxymethylcellulose and a polyol to the eye.
A method of manufacturing a dry eye composition comprising combining in an aqueous solution ophthalmically pure carboxy-containing polymer with ophthalmically pure polyol, wherein the carboxy-containing polymer has a molecular weight that is a minimum of about 90 kDa and a maximum of about 700 kDa and has a Mark-Houwink constant that is a minimum of about 0.6 and a maximum of about 1.5.
Dependencies are inferred from the claim text.