Peptide-based body surface coloring reagents
AssigneeE.I. du Pont de Nemours and Company
InventorsJohn O'Brien, Hong Wang, Ying Wu
Life of this patent
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Abstract
Peptides have been identified that bind with high affinity to body surfaces, such as, hair, skin, nails, teeth, gums, and oral cavity surfaces. Diblock and triblock peptide-based body surface coloring reagents formed by coupling a body surface binding peptide to a pigment binding peptide, either directly or through a spacer, are described. The peptide-based body surface coloring reagents may be used in conjunction with pigments to color body surfaces.
Claims32
A diblock, peptide-based body surface coloring reagent having the general structure [(BSBP)m−(PBP)n]x, wherein
- a) BSBP is a body surface binding peptide;
- b) PBP is a pigment-binding peptide;
- and
- c) m, n, and x independently range from 1 to about 10.
A triblock, peptide-based body surface coloring reagent having the general structure [[(BSBP)m−Sq]x−[(PBP)n−Sr]z]y, wherein
- a) BSBP is a body surface binding peptide;
- b) PBP is a pigment-binding peptide;
- c) S is a molecular spacer;
- and
- d) m, n, x and z independently range from 1 to about 10, y is from 1 to about 5, and where q and r are each independently 0 or 1, provided that both r and q may not be 0.
Dependencies are inferred from the claim text.