Buccal, polar and non-polar sprays containing propofol

An oral spray composition for transmucosal administration of propofol comprising:

• propofol in an amount of between about 1 and about 85 percent by weight of the total composition;
• a polar solvent in an amount between about 1 and about 85 percent by weight of the total composition;
• and
• a propellant in an amount between about 10 and about 90 percent by weight of the total composition, wherein said propellant comprises a C3 to C8 hydrocarbon of linear or branched configuration.

An oral spray composition for transmucosal administration of propofol comprising:

• propofol in an amount between about 1 and about 85 percent by weight of the total composition;
• and
• a non-polar solvent in an amount between about 1 and about 85 percent by weight of the total composition;
• and
• a propellant in an amount between about 10 and about 90 percent by weight of the total composition, wherein said propellant comprises a C3 to C8 hydrocarbon of linear or branched configuration.

An oral spray composition for transmucosal administration of propofol comprising:

• propofol in an amount between about 1 and about 80 percent by weight of the total composition;
• a polar solvent in an amount of between about 2 to about 80 percent by weight of the total composition;
• and
• a non-polar solvent in an amount of between about 1 to about 80 percent by weight of the total composition;
• and
• a propellant in an amount between about 10 to about 90 percent by weight of the total composition, wherein said propellant comprises a C3 to C8 hydrocarbon of linear or branched configuration.