Peptide-chelate conjugates
AssigneeGe Healthcare Limited
InventorsAlan Cuthbertson, Marivi Mendizabal, Mark Dixon, Anthony Storey, Edward Bacon, Vinay Desai, Sudahkar Kasina, Henry Wolfe
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Abstract
A peptide-chelate with affinity for the ST receptor is disclosed, wherein the chelate is tetradentate. The peptide-chelate conjugate of the invention may be labelled with a radiometal to provide a metal complex. A radiopharmaccutical composition comprising the metal complex is provided, which is suitable for the diagnostic imaging of colorectal cancer. Also provided for in the invention is a kit for the preparation of the radiopharmaceutical preparation.
Claims21
1) A peptide-chelate conjugate comprising a peptide having affinity for the ST receptor conjugated to a tetradentate chelating agent, wherein the peptide having affinity for the ST receptor comprises 10 to 25 amino acids.
Dependencies are inferred from the claim text.