Determination of the clinical state of a subject

An apparatus for ascertaining a clinical state of a subject, the apparatus comprising:

• means for acquiring a first measurement signal containing desired physiological information data reflecting the clinical state of the subject;
• first transform means for applying a first normalization transform to the first measurement signal, the first normalization transform being dependent on previously acquired history data, whereby the first transform means are configured to output a first normalized measurement signal having a predetermined value range;
• and
• indicator means for indicating the clinical state of the subject as an index which is dependent on the first normalized measurement signal.

An apparatus for ascertaining a Clinical state of a subject, the apparatus comprising:

• a measurement unit configured to acquire a first measurement signal from a subject, the first measurement signal containing desired physiological data reflecting the clinical state of the subject;
• a data processing unit configured to apply a first normalization transform to the first measurement signal, the first normalization transform being dependent on previously acquired history data, wherein the data processing unit is configured to output a first normalized measurement signal having a predetermined value range;
• and
• a display unit configured to display the clinical state of the subject as an index dependent on the first normalized measurement signal.

A computer program product for ascertaining a clinical state of a subject, the computer program product comprising:

• a first program code portion configured to retrieve physiological data reflecting the clinical state of the subject;
• a second program code portion configured to apply a first normalization transform to the physiological data, wherein the second program code portion is configured to output a first normalized measurement signal having a predetermined value range;
• and
• a third program code portion configured to indicate the clinical state of the subject as an index which is dependent on the first normalized measurement signal.

A method for controlling a clinical state of a subject, the method comprising the steps of:

• acquiring a first measurement signal containing physiological data reflecting the clinical state of the subject;
• applying a first normalization transform to the first measurement signal, the first normalization transform being dependent on previously acquired history data, whereby a first normalized measurement signal having a predetermined value range is obtained;
• forming a diagnostic index which is dependent on the first normalized measurement signal, the diagnostic index serving as a measure of the clinical state of the subject;
• and
• controlling administration of at least one drug to the patient, the controlling step being performed based on the diagnostic index.

A system for controlling a Clinical state of a subject, the system comprising:

• means for acquiring a first measurement signal containing first physiological data reflecting the clinical state of the subject;
• first transform means for applying a first normalization transform to the first measurement signal, the first normalization transform being dependent on previously acquired history data, whereby the first transform means are configured to output a first normalized measurement signal having a predetermined value range;
• drug delivery means for administering at least one drug to the patient;
• and
• control means for controlling the drug delivery means based on an index dependent which is on the first normalized measurement signal.